113-O12B
Based on 1 Customer Validation
113-O12B is a lymph node-specific ionizable cationic lipid. 113-O12B can be used in lipid nanoparticle-related research, such as LNP-based mRNA vaccine delivery.
For research use only. We do not sell to patients.
- Purity : 99.79%
- CAS No.: 2803699-72-9
- Formula: C57H111N3O8S8
- Molecular Weight:1223.03
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Protocols
- Purity & Documentation
- References
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Help & FAQs
![1,1′-Ethylidenebis[L-tryptophan]](https://file.medchemexpress.com/product_pic/hy-w585843.gif)
Biological Activity
Description
In Vitro
113-O12B-derived LNPs achieve selective enrichment of mRNA in lymph nodes without additional conjugation of targeting ligands[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2803699-72-9
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Appearance Liquid (Density: 1.095±0.06 g/cm3)
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Molecular Weight 1223.03
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Formula C57H111N3O8S8
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Color Colorless to light yellow
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SMILES
O=C(CCN(CCN(CCN(CCC(OCCSSCCCCCCCC)=O)CCC(OCCSSCCCCCCCC)=O)C)CCC(OCCSSCCCCCCCC)=O)OCCSSCCCCCCCC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (81.76 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Ethanol : 6.67 mg/mL (5.45 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Ethanol / DMSO | 1 mM | 0.8176 mL | 4.0882 mL | 8.1764 mL | 20.4410 mL |
| 5 mM | 0.1635 mL | 0.8176 mL | 1.6353 mL | 4.0882 mL | |
| DMSO | 10 mM | 0.0818 mL | 0.4088 mL | 0.8176 mL | 2.0441 mL |
| 15 mM | 0.0545 mL | 0.2725 mL | 0.5451 mL | 1.3627 mL | |
| 20 mM | 0.0409 mL | 0.2044 mL | 0.4088 mL | 1.0221 mL | |
| 25 mM | 0.0327 mL | 0.1635 mL | 0.3271 mL | 0.8176 mL | |
| 30 mM | 0.0273 mL | 0.1363 mL | 0.2725 mL | 0.6814 mL | |
| 40 mM | 0.0204 mL | 0.1022 mL | 0.2044 mL | 0.5110 mL | |
| 50 mM | 0.0164 mL | 0.0818 mL | 0.1635 mL | 0.4088 mL | |
| 60 mM | 0.0136 mL | 0.0681 mL | 0.1363 mL | 0.3407 mL | |
| 80 mM | 0.0102 mL | 0.0511 mL | 0.1022 mL | 0.2555 mL |
113-O12B Related Classifications
HY-W590681 Related Classifications
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