2803699-72-9
2803699-72-9
Chemical Structure
113-O12B
- CAS No.: 2803699-72-9
- Formula:C57H111N3O8S8
- Molecular Weight:1223.03
IUPAC Name: tetrakis(2-(octyldisulfanyl)ethyl) 3,3',3'',3'''-(((methylazanediyl)bis(ethane-2,1-diyl))bis(azanetriyl))tetrapropionate
InChIKey: YIMNDEVCHLNZOO-UHFFFAOYSA-N
SMILES: O=C(CCN(CCN(CCN(CCC(OCCSSCCCCCCCC)=O)CCC(OCCSSCCCCCCCC)=O)C)CCC(OCCSSCCCCCCCC)=O)OCCSSCCCCCCCC
Biological Activity: 113-O12B is a lymph node-specific ionizable cationic lipid. 113-O12B can be used in lipid nanoparticle-related research, such as LNP-based mRNA vaccine delivery[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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113-O12B | 99.79% | 113-O12B is a lymph node-specific ionizable cationic lipid. 113-O12B can be used in lipid nanoparticle-related research, such as LNP-based mRNA vaccine delivery. | ||||||||||||||||||||
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References
- [1]. Zhou F, et al. From structural design to delivery: mRNA therapeutics for cancer immunotherapy. Exploration (Beijing, China). 2024 Apr;4(2):20210146.
- [2]. Xia Y, et al. Application of Nano-Delivery Systems in Lymph Nodes for Tumor Immunotherapy. Nano-micro letters. 2023 Jun 03;15(1):145.
- [3]. Han J, et al. Lipid nanoparticle-based mRNA delivery systems for cancer immunotherapy. Nano convergence. 2023 Aug 07;10(1):36. [Content Brief]
- [4]. Taibi T, et al. mRNA-based therapeutic strategies for cancer treatment. Molecular therapy : the journal of the American Society of Gene Therapy. 2024 Sep 04;32(9):2819-2834.
