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Cat. No.: HY-W341505

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2,4-Dibromo-6-chlorophenol

Name: 2,4-Dibromo-6-chlorophenol
Brand: MedChemExpress
SKU: HY-W341505
Price: 36.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: 6-Chloro-2,4-dibromophenol)

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2,4-Dibromo-6-chlorophenol is a broad-spectrum halogenated phenolic antifungal agent that inhibits methicillin-resistant Staphylococcus aureus, Burkholderia cepacia, and marine biofouling bacteria, but has no inhibitory effect on Escherichia coli. 2,4-Dibromo-6-chlorophenol can be isolated from cultures of Pseudovibrio luteolus associated with Padina australis, and also exists as a chlorinated bromophenol transformation product during the aqueous chlorination of dibromophenol and as a phenolic halogenated disinfection byproduct in simulated chlorinated drinking water. 2,4-Dibromo-6-chlorophenol can be used in research on cystic fibrosis.

For research use only. We do not sell to patients.

CAS No.: 4526-56-1
Formula: C₆H₃Br₂ClO
Molecular Weight:286.35

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

2,4-Dibromo-6-chlorophenol Chemical Structure

CAS No.: 4526-56-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
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Biological Activity

Description

In Vitro

Bacterial InfectionOthers

Bacterial Infection

2,4-Dibromo-6-chlorophenol (1.0 mg/mL; 37 °C overnight) inhibits MRSA 9551, Burkholderia cepacia 5415, and marine biofouling strains 97003.5.1 and C1052 in the disk diffusion assay, with inhibition zones of 20-28 mm, but does not inhibit E. coli EMG 9^[2].
2,4-Dibromo-6-chlorophenol is derived from Pseudoalteromonas luteoviolacea associated with Padina australis and exhibits activity against Burkholderia cepacia and Methicillin-resistant (HY-121544) Staphylococcus aureus^[3].

Others

2,4-Dibromo-6-chlorophenol (31.3 μM; approximately 20 min) is formed as the major monochloro electrophilic substitution product during the aqueous chlorination of 2,4-DBP, reaching a maximum concentration of 31.3 μM at approximately 20 min, accounting for about 81% of the initial conversion^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

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Chemical Information

CAS No. 4526-56-1
Molecular Weight 286.35
Formula C₆H₃Br₂ClO
SMILES

C1=C(C=C(C(=C1Br)O)Cl)Br
Synonyms

6-Chloro-2,4-dibromophenol
Structure Classification
- Phenols
- Monophenols
Initial Source
- Microorganism
Pseudoalteromonas luteoviolacea
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Xiang W, et al. Transformation of bromophenols by aqueous chlorination and exploration of main reaction mechanisms. Chemosphere. 2021 Feb;265:129112.

[2]. Jiang Z, et al. Two Diketopiperazines and One Halogenated Phenol from Cultures of the Marine Bacterium, Pseudoalteromonas luteoviolacea . Natural Product Letters, 14(6), 435-440.

[3]. Singh RP, et al. Antimicrobial compounds from seaweeds-associated bacteria and fungi. Applied microbiology and biotechnology. 2015 Feb;99(4):1571-86.

[4]. Huang Y, et al. New phenolic halogenated disinfection byproducts in simulated chlorinated drinking water: Identification, decomposition, and control by ozone-activated carbon treatment. Water research. 2018 Dec 01;146:298-306.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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