4526-56-1
Chemical Structure
2,4-Dibromo-6-chlorophenol
Synonym(s): 6-Chloro-2,4-dibromophenol
- CAS No.: 4526-56-1
- Formula:C6H3Br2ClO
- Molecular Weight:286.35
IUPAC Name: 3,3'-difluoro-[1,1'-biphenyl]-4,4'-diamine
InChIKey: MQSIWVCWTVYFDP-UHFFFAOYSA-N
SMILES: C1=C(C=C(C(=C1Br)O)Cl)Br
Biological Activity: 2,4-Dibromo-6-chlorophenol is a broad-spectrum halogenated phenolic antifungal agent that inhibits methicillin-resistant Staphylococcus aureus, Burkholderia cepacia, and marine biofouling bacteria, but has no inhibitory effect on Escherichia coli. 2,4-Dibromo-6-chlorophenol can be isolated from cultures of Pseudovibrio luteolus associated with Padina australis, and also exists as a chlorinated bromophenol transformation product during the aqueous chlorination of dibromophenol and as a phenolic halogenated disinfection byproduct in simulated chlorinated drinking water. 2,4-Dibromo-6-chlorophenol can be used in research on cystic fibrosis[1][2][3][4].
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2,4-Dibromo-6-chlorophenol | 2,4-Dibromo-6-chlorophenol is a broad-spectrum halogenated phenolic antifungal agent that inhibits methicillin-resistant Staphylococcus aureus, Burkholderia cepacia, and marine biofouling bacteria, but has no inhibitory effect on Escherichia coli. 2,4-Dibromo-6-chlorophenol can be isolated from cultures of Pseudovibrio luteolus associated with Padina australis, and also exists as a chlorinated bromophenol transformation product during the aqueous chlorination of dibromophenol and as a phenolic halogenated disinfection byproduct in simulated chlorinated drinking water. 2,4-Dibromo-6-chlorophenol can be used in research on cystic fibrosis. | |||||||||||||||||||||
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References
- [1]. Xiang W, et al. Transformation of bromophenols by aqueous chlorination and exploration of main reaction mechanisms. Chemosphere. 2021 Feb;265:129112.
- [2]. Jiang Z, et al. Two Diketopiperazines and One Halogenated Phenol from Cultures of the Marine Bacterium, Pseudoalteromonas luteoviolacea . Natural Product Letters, 14(6), 435-440.
- [3]. Singh RP, et al. Antimicrobial compounds from seaweeds-associated bacteria and fungi. Applied microbiology and biotechnology. 2015 Feb;99(4):1571-86.
- [4]. Huang Y, et al. New phenolic halogenated disinfection byproducts in simulated chlorinated drinking water: Identification, decomposition, and control by ozone-activated carbon treatment. Water research. 2018 Dec 01;146:298-306.
