3-Fluoro-L-tyrosine
Based on 1 Customer Validation
3-Fluoro-L-tyrosine is a tyrosine analog that inhibits the transamination of tyrosine transaminase (TAT). 3-Fluoro-L-tyrosine can be biologically incorporated into proteins in place of tyrosine. 3-Fluoro-L-tyrosine can mimic the substrate of rat liver tyrosine transaminase, markedly disrupting the tyrosine-TAT association. 3-Fluoro-L-tyrosine is useful for research related to tumors and tyrosine metabolism disorders.
For research use only. We do not sell to patients.
- Purity : 99.89%
- CAS No.: 7423-96-3
- Formula: C9H10FNO3
- Molecular Weight:199.18
-
Storage:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Description
In Vitro
3-Fluoro-L-tyrosine (1 mM) is added to the E. coli BL21 (DE3) ΔtyrA::Tn10 (BU80) culture system after Tyr depletion, globally replacing Tyr for incorporation into recombinant Rho 1,2-CTD to obtain soluble m-FY-1,2-CTD[2].
3-Fluoro-L-tyrosine is converted to 3-fluoro-4-hydroxyphenylglycine, which is incorporated into multiple positions within Enduracidin (HY-131093)[4].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 7423-96-3
-
Appearance Solid
-
Molecular Weight 199.18
-
Formula C9H10FNO3
-
Color White to off-white
-
SMILES
C1=CC(=C(C=C1C[C@@H](C(=O)O)N)F)O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
In Vitro:
H2O : 2 mg/mL (10.04 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (281 KB)
-
SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.0206 mL | 25.1029 mL | 50.2058 mL | 125.5146 mL |
| 5 mM | 1.0041 mL | 5.0206 mL | 10.0412 mL | 25.1029 mL | |
| 10 mM | 0.5021 mL | 2.5103 mL | 5.0206 mL | 12.5515 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
3-Fluoro-L-tyrosine Related Classifications
HY-W104477 Related Classifications
Powered by Bioz