IKK-β Activator
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β-1,3-Glucan
0 ImagesSynonyms: β Glucanβ-1,3-Glucan (β Glucan) is an orally active polysaccharide composed of glucose polymers. β-1,3-Glucan increase the activity of IKKβ kinase, enhances the production of nitric oxide. β-1,3-Glucan improves resistance to Vibrio harveyi infection. β-1,3-Glucan enhances immune response, promotes blood pressure recovery, reduces lung, kidney and liver damage, inhibits the growth of syngeneic tumors.
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SMU-H1
0 ImagesCat. No.: HY-189658CAS No.: 2410782-67-9SMU-H1 is a TLR2 agonist with a KD of 12.1 nM for mouse TLR2 and an EC50 of 5.14 nM in HEK-Blue hTLR2 cells. SMU-H1 binds TLR2 and activates MyD88-dependent signaling. SMU-H1 activates the NF-κB and MAPK signaling pathways. SMU-H1 induces proinflammatory cytokine production. SMU-H1 promotes M1 macrophage polarization and dendritic cell activation. SMU-H1 can be used for research on Lewis lung cancer.
