IRE1α Activator
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SH458
0 ImagesCat. No.: HY-189694CAS No.: 3109470-77-8SH458 is an orally active anti-triple-negative breast cancer compound. SH458 significantly upregulates the expression of unfolded protein response (UPR)-related proteins, including p-eIF2α and p-IRE1α. SH458 induces Apoptosis, G2/M phase arrest, oxidative stress with increased ROS, DNA damage, and checkpoint kinase activation.
