country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-126295

Copy Link Print Information

MMV367

Name: MMV367
Brand: MedChemExpress
SKU: HY-126295
Availability: PreOrder

(Synonyms: GSK3772701; Anti-parasitic agent 3)

MMV367 is an orally effective inhibitor of Plasmodium falciparum acyl coenzyme A synthetase 10/11. MMV367 interferes with acyl coenzyme A synthetase function and parasite metabolism. MMV367 exhibits rapid parasiticidal activity and antimalarial effects against blood-stage Plasmodium falciparum, with no cross-resistance to existing antimalarial agents. MMV367 can be used in research related to Plasmodium falciparum malaria.

For research use only. We do not sell to patients.

CAS No.: 2366983-10-8
Formula: C₂₁H₂₂FN₅O₃
Molecular Weight:411.43

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (275 KB)

MMV367 Chemical Structure

CAS No.: 2366983-10-8

Size

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

IC₅₀ & Target

^[1]

Plasmodium

All Parasite Isoforms :

In Vitro

Parasitic Infection

MMV367 (72 h) does not lead to reduced in vitro susceptibility of the exposed P. falciparum parasite strains in the growth inhibition assay compared with the 3D7-A parental strain^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2366983-10-8
Molecular Weight 411.43
Formula C₂₁H₂₂FN₅O₃
SMILES

O=C(C1=CC=C(OC[C@H](O)CN2N=CN=N2)C=C1)N(CC3)C[C@H]3C4=CC=C(F)C=C4
Synonyms

GSK3772701; Anti-parasitic agent 3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (275 KB)
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Barber B E, et al. The pyrrolidinamide antimalarial drug MMV367 rapidly clears blood-stage Plasmodium falciparum in healthy adults with experimental malaria[J]. Science Translational Medicine, 2026, 18(853): eaec1863.

[2]. Kuemmerle A, et al. First-in-human safety, tolerability, pharmacokinetics and pilot food-effect study of the candidate antimalarial compound MMV367. British journal of clinical pharmacology. 2025 Jun;91(6):1821-1833.

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

MOQ

Minimum order quantity

100 mg

Get Quote In-stock

Other size

Get Quote

Amount: USD 0.00

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Product Name:
CAS No.:
Species:
Purity:
Quantity:

MMV367

All Parasite Isoforms