Azumolene sodium
Based on 3 publication(s) in Google Scholar
Azumolene sodium (EU4093) is an analog of Dantrolene (HY-12542) that inhibits malignant hyperthermia (MH) syndrome and intracellular Ca2+ homeostasis failure caused by Halothane (HY-B1010)/Succinylcholine. Azumolene sodium (0.5-2.0 mg/kg) reduces [Ca2+]i (from 207 nM to 38 nM) in MH-susceptible skeletal muscle following intramuscular injection.
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- CAS No.: 105336-14-9
- Formula: C13H9BrN4NaO3
- Molecular Weight:372.13
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications Citing Use of MedChemExpress (MCE) Azumolene sodium
MoreAll Calcium Channel Isoforms
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Biological Activity
Description
Chemical Information
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CAS No. 105336-14-9
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Molecular Weight 372.13
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Formula C13H9BrN4NaO3
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SMILES
O=C1NC(CN1/N=C/C2=NC=C(C3=CC=C(Br)C=C3)O2)=O.[Na]
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Synonyms
EU4093
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (3)
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Journal Impact Factor
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Most Recent
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Nat Commun
Crystal structures of Ryanodine Receptor reveal dantrolene and azumolene interactions guiding inhibitor development. [Abstract]2025 Nov 18;16(1):10110. PMID: 41253812 -
Cell Death Dis
Pathological convergence of APP and SNCA deficiency in hippocampal degeneration of young rats. [Abstract]2023 May 13;14(5):325. PMID: 37179386 -
Small
2025 Mar;21(12):e2408139. PMID: 40012250
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)