100-95-8
Chemical Structure
Metalkonium chloride
Synonym(s): Dodecarbonium chloride
- CAS No.: 100-95-8
- Formula:C23H41ClN2O
- Molecular Weight:397.04
IUPAC Name: N-benzyl-2-(dodecylamino)-N,N-dimethyl-2-oxoethan-1-aminium chloride
InChIKey: COLOBWZNRYGBRU-UHFFFAOYSA-N
SMILES: [Cl-].O=C(NCCCCCCCCCCCC)C[N+](C)(C)CC=1C=CC=CC1
Biological Activity: Metalkonium chloride (Dodecarbonium chloride) is a quaternary ammonium salt, surfactant, and transdermal penetration enhancer. Metalkonium chloride increases skin permeability to facilitate transdermal delivery. Metalkonium chloride enhances the growth inhibitory activity of Nystatin (HY-17409) ointment against C. monosa. Metalkonium chloride can be used in studies related to Candida monosa infections[1][2].
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Metalkonium chloride | Metalkonium chloride (Dodecarbonium chloride) is a quaternary ammonium salt, surfactant, and transdermal penetration enhancer. Metalkonium chloride increases skin permeability to facilitate transdermal delivery. Metalkonium chloride enhances the growth inhibitory activity of Nystatin (HY-17409) ointment against C. monosa. Metalkonium chloride can be used in studies related to Candida monosa infections. | |||||||||||||||||||||
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References
- [1]. David Fikstad, et al. Using quaternary ammonium salts for transdermal drug delivery. WO2001017472A1. WIPO (PCT). 2000-09-08.
- [2]. Petricic V, et al. Influence of matrix composition on the release of nystatin from topical dosage forms and on its efficiency against Candida monosa[J]. ACTA PHARMACEUTICA JUGOSLAVICA, 1982, 32(3): 209-217.
