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Cat. No.: HY-113819

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Metalkonium chloride

Name: Metalkonium chloride
Brand: MedChemExpress
SKU: HY-113819
Availability: PreOrder

(Synonyms: Dodecarbonium chloride)

Metalkonium chloride (Dodecarbonium chloride) is a quaternary ammonium salt, surfactant, and transdermal penetration enhancer. Metalkonium chloride increases skin permeability to facilitate transdermal delivery. Metalkonium chloride enhances the growth inhibitory activity of Nystatin (HY-17409) ointment against C. monosa. Metalkonium chloride can be used in studies related to Candida monosa infections.

For research use only. We do not sell to patients.

CAS No.: 100-95-8
Formula: C₂₃H₄₁ClN₂O
Molecular Weight:397.04

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Metalkonium chloride Chemical Structure

CAS No.: 100-95-8

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Biological Activity

Description

In Vitro

Fungal Infection

Metalkonium chloride enhances the growth inhibitory activity of Nystatin (HY-17409) ointment against Candida monosa^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Transepithelial/transendothelial electrical resistance assay

Chemical Information

CAS No. 100-95-8
Molecular Weight 397.04
Formula C₂₃H₄₁ClN₂O
SMILES

[Cl-].O=C(NCCCCCCCCCCCC)C[N+](C)(C)CC=1C=CC=CC1
Synonyms

Dodecarbonium chloride
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. David Fikstad, et al. Using quaternary ammonium salts for transdermal drug delivery. WO2001017472A1. WIPO (PCT). 2000-09-08.

[2]. Petricic V, et al. Influence of matrix composition on the release of nystatin from topical dosage forms and on its efficiency against Candida monosa[J]. ACTA PHARMACEUTICA JUGOSLAVICA, 1982, 32(3): 209-217.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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