127902-98-1
127902-98-1
Chemical Structure
Staphyloferrin A
- CAS No.: 127902-98-1
- Formula:C17H24N2O14
- Molecular Weight:480.38
InChIKey: VJSIXUQLTJCRCS-INUFPEASSA-N
SMILES: OC(C[C@@](C(O)=O)(O)CC(N[C@@H](C(O)=O)CCCNC(C[C@](C(O)=O)(O)CC(O)=O)=O)=O)=O
Biological Activity: Staphyloferrin A is a carboxylate-type siderophore, as well as an iron (III) chelator and a HtsA ligand with high binding affinity for iron (III). Staphyloferrin A can be used in studies of bacterial infections[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Staphyloferrin A | 95.0% | Staphyloferrin A is a carboxylate-type siderophore, as well as an iron (III) chelator and a HtsA ligand with high binding affinity for iron (III). Staphyloferrin A can be used in studies of bacterial infections. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Schizokinen | Schizokinen is an iron-transport agent. Schizokinen can be obtained from Bacillus megaterium. Schizokinen possesses a higher affinity for iron(III) than Desferrioxamine B. Schizokinen reduces the division lag of bacteria. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Aerobactin (Standard) | ≥98% | Aerobactin (Standard) is the analytical standard of Aerobactin (HY-122280). This product is intended for research and analytical applications. Aerobactin is a siderophore produced by bacteria. Aerobactin exhibits the primary activity of chelating ferric ions and transporting them into bacterial cells. Aerobactin promotes bacterial growth, biofilm formation, antioxidant stress resistance, and enhances bacterial virulence and transcellular translocation ability under iron-deficient conditions. Aerobactin is used in research on bacterial infections. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Rhizoferrin | 99.79% | Rhizoferrin is a siderophore, which can be isolated from Rhizopus microsporus. Rhizoferrin binds iron ions with high affinity, and can be used as an effective iron source. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
L-NMMA citrate | L-NMMA (Tilarginine) citrate is a non-selective and competitive inhibitor of nitric oxide synthase. L-NMMA citrate inhibits three subtypes, namely nNOS, eNOS, and iNOS, and reduces NO production. L-NMMA citrate alleviates mechanical allodynia, thermal hyperalgesia, and choroidal fibrosis. L-NMMA citrate is applicable to research related to nociception, bone cancer pain, and myopia. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Arthrobactin | Arthrobactin is a ferric ionophore that can be produced by Arthrobacter pascens. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
β-Citryl-L-glutamic acid | 98.0% | β-Citryl-L-glutamic acid (β-Citrylglutamic acid) is a citrylglutamic acid, that can be isolated from newborn rat brain. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
α2β1 Integrin Ligand Peptide | 98.84% | α2β1 Integrin Ligand Peptide interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular signals into cells. It is a potential antagonist of collagen receptors. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
TriDAP | TriDAP (L-Ala-γ-D-Glu-meso-diaminopimelic acid) is a NOD1 agonist with a Kd value of 34.5 μM. TriDAP enhances the binding of NOD1-RICK, promotes RICK phosphorylation, and activates the NF-κB, TAK1, MEK/ERK, p38 and interferon response pathways. TriDAP downregulates Runx2 via increasing ubiquitination and reduces trabecular bone parameters. TriDAP decreases IκBα levels and increases p65 levels. TriDAP induces the secretion of proinflammatory mediators IL-8 and prostaglandins, triggers tissue inflammation and innate immune activation, and inhibits SARS-CoV-2 replication in lung epithelial cells. TriDAP increases the RANKL/OPG ratio in mice, reduces bone mass and enhances osteoclast activity, and inhibits new bone formation by decreasing the mineralization deposition rate in mice. TriDAP can be used in research related to pulpitis, chronic ulcerative colitis, Crohn's disease and SARS-CoV-2 infection. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
C12-iE-DAP | C12-iE-DAP (Lauroyl-γ-D-glutamyl-meso-diaminopimelic acid) is a highly potent and selective NOD1 agonist, with an EC50 of 0.027 nM in HEK-Blue cells expressing human NOD1. C12-iE-DAP activates the NOD1/RIPK2 signaling pathway and its downstream p38 MAPK and NF-κB, induces the expression of inflammatory mediators such as IL6 and IL8, and exerts synergistic effects with TLR4, Dectin-1 or Mincle signaling. C12-iE-DAP can be used in studies related to vascular inflammation, tumor metastasis and neuroinflammation. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
FK-565 | 99.88% | FK-565 is a synthetic immunomodulatory peptide with a nucleotide oligomerization domain-1 (NOD1) ligand. FK-565 can activate macrophages, NK cells, and peritoneal exudative cells, enhancing the innate immune response. FK-565 has antiviral activity against a variety of viruses in vivo, and its effect is achieved through immunomodulation rather than direct viral inhibition. FK-565 can induce mouse models of arteritis and coronary arteritis (Kawasaki disease-like disease) through a NOD1-mediated mechanism. FK-565 can be used for research on viral infections and inflammatory vascular diseases. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
