133-26-6
133-26-6
Chemical Structure
Peucedanin
- CAS No.: 133-26-6
- Formula:C15H14O4
- Molecular Weight:258.27
IUPAC Name: 2-isopropyl-3-methoxy-7H-furo[3,2-g]chromen-7-one
InChIKey: YQBNJPACAUPNLV-UHFFFAOYSA-N
SMILES: O=C1C=CC2=CC3=C(OC(C(C)C)=C3OC)C=C2O1
Biological Activity: Peucedanin is an orally active insect growth inhibitor and coumarin compound. Peucedanin reduces Hsp27 and Hsp72 expression and blocks Ca2+ channel activity. Peucedanin induces Apoptosis and necrosis. Peucedanin reduces the relative growth rate and consumption rate of Spodoptera littoralis larvae. Peucedanin can be used in research on cervical cancer[1][2][3].
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Peucedanin | Peucedanin is an orally active insect growth inhibitor and coumarin compound. Peucedanin reduces Hsp27 and Hsp72 expression and blocks Ca2+ channel activity. Peucedanin induces Apoptosis and necrosis. Peucedanin reduces the relative growth rate and consumption rate of Spodoptera littoralis larvae. Peucedanin can be used in research on cervical cancer. | |||||||||||||||||||||
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References
- [1]. Hadaček F, et al. Analysis, isolation and insecticidal activity of linear furanocoumarins and other coumarin derivatives fromPeucedanum (Apiaceae: Apioideae). Journal of chemical ecology. 1994 Aug;20(8):2035-54. [Content Brief]
- [2]. Bartnik M,, et al. Effect of peucedanin and bergapten (5-MOP), furanocoumarins isolated from Peucedanum tauricum Bieb.(Apiaceae) fruits, on apoptosis induction and heat-shock protein expression in HeLa cells[J]. Herba Pol, 2006, 52: 71-78.
- [3]. Bartnik M, et al. Single crystal X-ray diffraction, spectroscopic and mass spectrometric studies of furanocoumarin peucedanin. Natural product communications. 2014 Jan;9(1):71-4.
