1335151-56-8
Chemical Structure
Coppersensor-3
- CAS No.: 1335151-56-8
- Formula:C32H56BN3O2S4
- Molecular Weight:653.88
IUPAC Name: N-((2,8-diethyl-5,5-dimethoxy-1,3,7,9-tetramethyl-5H-4l4,5l4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-10-yl)methyl)-2-((2-(ethylthio)ethyl)thio)-N-(2-((2-(ethylthio)ethyl)thio)ethyl)ethan-1-amine
InChIKey: UIVWBUDYTQFONA-UHFFFAOYSA-N
SMILES: C[O-][B+3]1([N]2=C(C)C(CC)=C(C)C2=C(CN(CCSCCSCC)CCSCCSCC)C3=C(C)C(CC)=C(C)[N-]31)[O-]C
Biological Activity: Coppersensor-3 is a Cu (I)-selective fluorescent probe, λabs 540 nm, λem 548 nm. Coppersensor-3 detects basal levels of labile Cu (I) in living cells and produces fluorescence turn-on by inhibiting photoinduced electron transfer. Coppersensor-3 is useful for studies related to copper homeostasis and copper transport[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Coppersensor-3 | 95.0% | Coppersensor-3 is a Cu (I)-selective fluorescent probe, λabs 540 nm, λem 548 nm. Coppersensor-3 detects basal levels of labile Cu (I) in living cells and produces fluorescence turn-on by inhibiting photoinduced electron transfer. Coppersensor-3 is useful for studies related to copper homeostasis and copper transport. | ||||||||||||||||||||
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References
- [1]. Cotruvo JA, et al. Synthetic fluorescent probes for studying copper in biological systems. Chemical Society reviews. 2015 Jul 07;44(13):4400-14. [Content Brief]
- [2]. Aron AT, et al. Recognition- and reactivity-based fluorescent probes for studying transition metal signaling in living systems. Accounts of chemical research. 2015 Aug 18;48(8):2434-42.
- [3]. Lu J, et al. Copper regulates the host innate immune response against bacterial infection via activation of ALPK1 kinase. Proceedings of the National Academy of Sciences. 2024 Jan 23;121(4):e2311630121.
- [4]. Lu J, et al. Copper regulates the host innate immune response against bacterial infection via activation of ALPK1 kinase. Proceedings of the National Academy of Sciences of the United States of America. 2024 Jan 23;121(4):e2311630121.
