1345412-48-7
1345412-48-7
Chemical Structure
Anti-inflammatory agent 99
- CAS No.: 1345412-48-7
- Formula:C16H12F2O2
- Molecular Weight:274.26
InChIKey: VOKHWXOGLWFVJX-MDZDMXLPSA-N
SMILES: O=C(C1=CC=C(C=C1)OC)/C=C/C2=C(C=CC=C2F)F
Biological Activity: Anti-inflammatory agent 99 is a chalcone derivative. Anti-inflammatory agent 99 inhibits LPS (HY-D1056)-induced NF-κB nuclear translocation and suppress the phosphorylation of JNK, ERK, and p38. Anti-inflammatory agent 99 inhibits the expression of cytoinflammatory factors such as TNF-α and IL-6 induced by LPS. Anti-inflammatory agent 99 can be used for the research of LPS-induced septic shock[1].
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Anti-inflammatory agent 99 | Anti-inflammatory agent 99 is a chalcone derivative. Anti-inflammatory agent 99 inhibits LPS (HY-D1056)-induced NF-κB nuclear translocation and suppress the phosphorylation of JNK, ERK, and p38. Anti-inflammatory agent 99 inhibits the expression of cytoinflammatory factors such as TNF-α and IL-6 induced by LPS. Anti-inflammatory agent 99 can be used for the research of LPS-induced septic shock. | |||||||||||||||||||||
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