1352090-52-8
1352090-52-8
Chemical Structure
NC9
Synonym(s): Cbz-Lys(Acr)-PEG2-dansyl
- CAS No.: 1352090-52-8
- Formula:C35H47N5O8S
- Molecular Weight:697.84
IUPAC Name: benzyl (S)-(1-((5-(dimethylamino)naphthalene)-1-sulfonamido)-10,17-dioxo-3,6-dioxa-9,16-diazanonadec-18-en-11-yl)carbamate
InChIKey: PEXQGECJXSNLDT-PMERELPUSA-N
SMILES: O=C(OCC1=CC=CC=C1)N[C@@H](CCCCNC(C=C)=O)C(NCCOCCOCCNS(=O)(C2=C3C=CC=C(N(C)C)C3=CC=C2)=O)=O
Biological Activity: NC9 (Cbz-Lys(Acr)-PEG2-dansyl) is an irreversible transglutaminase (TG) inhibitor. NC9 inhibits osteoblast differentiation and mineralization. NC9 destabilizes microtubules. NC9 can be used for the research of osteoblast differentiation[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NC9 | 99.98% | NC9 (Cbz-Lys(Acr)-PEG2-dansyl) is an irreversible transglutaminase (TG) inhibitor. NC9 inhibits osteoblast differentiation and mineralization. NC9 destabilizes microtubules. NC9 can be used for the research of osteoblast differentiation. | ||||||||||||||||||||
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MC3482 | 98.55% | MC3482 is a specific sirtuin5 (SIRT5) inhibitor. | ||||||||||||||||||||
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Dansylphenylalanine | 99.65% | Dansylphenylalanine is a phenylalanine derivative. | ||||||||||||||||||||
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TG2 inhibitor VA4 | 99.66% | TG2 inhibitor VA4 (compound VA4) is an irreversible Type 2 transglutaminase (TG2) inhibitor. TG2 inhibitor VA4 reacts exclusively at the TG2 transamidase site, inhibits both transamidase and GTP-binding activities. | ||||||||||||||||||||
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AA9 | AA9 is a potent Transglutaminase 2 (TG2) inhibitor. AA9 strongly impacts HIF-mediated hypoxia in MDA-MB-231 cells. | |||||||||||||||||||||
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ST-148 maleate | 99.4% | ST-148 maleate is a potent and orally active DENV inhibitor. ST-148 maleate shows antiviral efficacy and low cell toxicity. ST-148 alters the interaction between lipid droplets and the C protein, thereby inhibiting viral replication.. | ||||||||||||||||||||
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Dansyl-Tyr-Val-Gly | 99.53% | Dansyl-Tyr-Val-Gly is a substrate of peptidylglycine monooxygenase (PHM), with a KD of 22 μM for PHM. Dansyl-Tyr-Val-Gly can be used to investigate the catalytic mechanism, kinetics and inactivation characteristics of PHM. | ||||||||||||||||||||
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Z-Arg-Arg-βNA acetate | 99.77% | Z-Arg-Arg-βNA acetate is a sensitive dipeptide substrate of the protease Cathepsin B and resistant to proteases H and L. Z-Arg-Arg-βNA acetate can serve as an important tool for distinguishing non-Cathepsin B type proteins. | ||||||||||||||||||||
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Z-Arg-Arg-4MβNA | ||||||||||||||||||||||
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Dansyl-D-Ala-Gly-Phe(pNO2)-Gly | 99.73% | Dansyl-D-Ala-Gly-Phe(pNO2)-Gly is a synthetic peptide substrate. As a substrate of NEP, Dansyl-D-Ala-Gly-Phe(pNO2)-Gly can be specifically recognized and cleaved by the enzyme, thereby releasing the fluorophore dansyl, which can be quantitatively detected. Therefore, it is often used to determine the activity of NEP. | ||||||||||||||||||||
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N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N6-((5-(dimethylamino)naphthalen-1-yl)sulfonyl)-L-lysine | 95.00% | N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N6-((5-(dimethylamino)naphthalen-1-yl)sulfonyl)-L-lysine is a lysine derivative. | ||||||||||||||||||||
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