1356837-92-7
1356837-92-7
Chemical Structure
Ramiprilat-d5 (Mixture of Diastereomers)
- CAS No.: 1356837-92-7
- Formula:C21H23D5N2O5
- Molecular Weight:393.49
IUPAC Name: (2S,3aR,6aR)-1-(((S)-1-carboxy-3-(phenyl-d5)propyl)-L-alanyl)octahydrocyclopenta[b]pyrrole-2-carboxylic acid
InChIKey: KEDYTOTWMPBSLG-WVRDEORASA-N
SMILES: [2H]C1=C([2H])C([2H])=C([2H])C([2H])=C1CC[C@@H](C(O)=O)N[C@@H](C)C(N2[C@@]3([H])[C@@](CCC3)([H])C[C@H]2C(O)=O)=O
Biological Activity: Ramiprilat-d5 (Mixture of Diastereomers) is the deuterium labeled Ramiprilat (Mixture of Diastereomers)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Ramiprilat-d5 (Mixture of Diastereomers) | Ramiprilat-d5 (Mixture of Diastereomers) is the deuterium labeled Ramiprilat (Mixture of Diastereomers). | |||||||||||||||||||||
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Ramiprilat (Standard) | 96.61% | Ramiprilat (Standard) (HOE 498 diacid (Standard)) is the analytical standard of Ramiprilat (HY-A0115). This product is intended for research and analytical applications. Ramiprilat (HOE 498 diacid), an active metabolite of Ramipril, is a potent and orally active angiotensin converting enzyme (ACE) inhibitor with a Ki value of 7 pM. Ramiprilat has acute antlhypertensive effect. Ramiprilat can be used for high blood pressure and heart failure research. | ||||||||||||||||||||
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Ramiprilat-d4 hydrochloride | Ramiprilat-d4 hydrochloride is deuterated labeled Ramiprilat (HY-A0115). Ramiprilat (HOE 498 diacid), an active metabolite of Ramipril, is a potent and orally active angiotensin converting enzyme (ACE) inhibitor with a Ki value of 7 pM. Ramiprilat can be used for high blood pressure and heart failure research. | |||||||||||||||||||||
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Ramiprilat-d5 | 98.33% | Ramiprilat-d5 is deuterium labeled Ramiprilat. Ramiprilat (HOE 498 diacid), an active metabolite of Ramipril, is a potent and orally active angiotensin converting enzyme (ACE) inhibitor with a Ki value of 7 pM. Ramiprilat can be used for high blood pressure and heart failure research. | ||||||||||||||||||||
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Ramiprilat-d3 (Mixture of Diastereomers) | Ramiprilat-d3 (Mixture of Diastereomers) is the deuterium labeled Ramiprilat (Mixture of Diastereomers). | |||||||||||||||||||||
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Ramiprilat | 97.09% | Ramiprilat (HOE 498 diacid), an active metabolite of Ramipril, is a potent and orally active angiotensin converting enzyme (ACE) inhibitor with a Ki value of 7 pM. Ramiprilat has acute antlhypertensive effect. Ramiprilat can be used for high blood pressure and heart failure research. | ||||||||||||||||||||
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Trandolaprilate | Trandolaprilate is a potent angiotensin-converting enzyme (ACE) inhibitor. Trandolaprilate partially inhibits angiotensin-I-mediated c-fos induction. Trandolaprilate is main bioactive metabolite of Trandolapril. Trandolaprilate shows high lipophilicity. | |||||||||||||||||||||
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Trandolaprilate hydrate | 97.30% | Trandolaprilate hydrate is a potent angiotensin-converting enzyme (ACE) inhibitor. Trandolaprilate hydrate partially inhibits angiotensin-I-mediated c-fos induction. Trandolaprilate is main bioactive metabolite of Trandolapril. Trandolaprilate shows high lipophilicity. | ||||||||||||||||||||
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Ramipril | 99.39% | Ramipril (HOE-498) is an orally active angiotensin-converting enzyme (ACE) inhibitor with blood-brain barrier permeability, and it is metabolized in vivo to the active metabolite Ramiprilat (HY-A0115). Ramipril has antioxidant, vasoprotective, and anti-atherosclerotic effects. Ramipril reduces the degradation of angiotensin II and bradykinin, downregulates TGF-beta/CTGF/fibronectin/α-SMA, and inhibits pancreatic/cardiac fibrosis. Ramipril improves glucose tolerance and insulin secretion, and reduces weight gain/appetite. Ramipril sensitizes mast cells, enhances FcεRI histamine release/degranulation, aggravates IgE allergic reactions, and downregulates the bradykinin receptor. Ramipril improves vascular endothelial relaxation function in spontaneously hypertensive rats. Ramipril alleviates Oxaliplatin (HY-17371)-induced acute hyperalgesia in mice. Ramipril can be used in research related to diseases such as type 2 diabetes, rheumatoid arthritis, allergy, and hypertension. | ||||||||||||||||||||
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Ramipril impurity 11 | Ramipril impurity 11 is an impurity of Ramipril. | |||||||||||||||||||||
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Ramipril impurity 1 | Ramipril impurity 1 (Ramipril methyl ester) is an impurity of Ramipril. | |||||||||||||||||||||
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Ramipril impurity 6 | Ramipril impurity 6 (Ramipril isopropyl ester) is an impurity of Ramipril. | |||||||||||||||||||||
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Ramipril impurity 8 | Ramipril impurity 8 is an impurity of Ramipril. | |||||||||||||||||||||
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Ramipril impurity 9 | Ramipril impurity 9 is an impurity of Ramipril. | |||||||||||||||||||||
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Ramipril impurity 2 | Ramipril impurity 2 (ent-Ramipril) is an impurity of Ramipril. | |||||||||||||||||||||
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