1360461-69-3
1360461-69-3
Chemical Structure
DOBAQ
- CAS No.: 1360461-69-3
- Formula:C49H83NO6
- Molecular Weight:782.19
IUPAC Name: N4-((5-(3-bromophenyl)thiophen-2-yl)methyl)-N2-isobutylpyrimidine-2,4-diamine
InChIKey: NYZTVPYNKWYMIW-WRBBJXAJSA-N
SMILES: CCCCCCCC/C=C\CCCCCCCC(OCC(OC(CCCCCCC/C=C\CCCCCCCC)=O)C[N+](C)(C)CC1=CC=C(C=C1)C([O-])=O)=O
Biological Activity: DOBAQ is a synthetic pH-sensitive zwitterionic lipid and cationic lipid nanoparticle component. DOBAQ can be used for siRNA delivery and mRNA delivery research[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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DOBAQ | 99.96% | DOBAQ is a synthetic pH-sensitive zwitterionic lipid and cationic lipid nanoparticle component. DOBAQ can be used for siRNA delivery and mRNA delivery research. | ||||||||||||||||||||
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References
- [1]. Staufer O, et al. Microfluidic production and characterization of biofunctionalized giant unilamellar vesicles for targeted intracellular cargo delivery. Biomaterials. 2021 Jan;264:120203. [Content Brief]
- [2]. Lou G, et al. Delivery of self-amplifying mRNA vaccines by cationic lipid nanoparticles: The impact of cationic lipid selection. Journal of Controlled Release. 2020 Sep 10;325:370-9.
- [3]. Walsh CL, et al. Synthesis and characterization of novel zwitterionic lipids with pH-responsive biophysical properties. Chemical communications (Cambridge, England). 2012 Jun 07;48(45):5575-7.
- [4]. Lussier F, et al. pH-Triggered Assembly of Endomembrane Multicompartments in Synthetic Cells. ACS synthetic biology. 2022 Jan 21;11(1):366-382.
