1365694-03-6
Chemical Structure
17(R)-Protectin D1
Synonym(s): 17-epi-Protectin D1
- CAS No.: 1365694-03-6
- Formula:C22H32O4
- Molecular Weight:360.49
IUPAC Name: (4Z,7Z,10R,11E,13E,15Z,17R,19Z)-10,17-dihydroxydocosa-4,7,11,13,15,19-hexaenoic acid
InChIKey: CRDZYJSQHCXHEG-HBMALMRFSA-N
SMILES: CC/C=C\C[C@@H](O)/C=C\C=C\C=C\[C@H](O)C/C=C\C/C=C\CCC(O)=O
Biological Activity: 17(R)-Protectin D1 (17-epi-Protectin D1) is a protectin-family-specific pro-resolving lipid mediator derived from DHA (HY-B2167) and generated via Aspirin (HY-14654) triggering, possessing pro-inflammatory resolution, neuroprotective, and other activities. 17(R)-Protectin D1 is also the 17R-epimer of Protectin D1 (HY-130413). 17(R)-Protectin D1 enhances macrophage phagocytosis of Escherichia coli and limits neutrophil infiltration. 17(R)-Protectin D1 attenuates stroke severity in animal models. 17(R)-Protectin D1 can be used in research related to peritonitis and stroke[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
17(R)-Protectin D1 | 17(R)-Protectin D1 (17-epi-Protectin D1) is a protectin-family-specific pro-resolving lipid mediator derived from DHA (HY-B2167) and generated via Aspirin (HY-14654) triggering, possessing pro-inflammatory resolution, neuroprotective, and other activities. 17(R)-Protectin D1 is also the 17R-epimer of Protectin D1 (HY-130413). 17(R)-Protectin D1 enhances macrophage phagocytosis of Escherichia coli and limits neutrophil infiltration. 17(R)-Protectin D1 attenuates stroke severity in animal models. 17(R)-Protectin D1 can be used in research related to peritonitis and stroke. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Hamidzadeh K, et al. A newly synthesized 17-epi-NeuroProtectin D1/17-epi-Protectin D1: Authentication and functional regulation of Inflammation-Resolution. Biochemical pharmacology. 2022 Sep;203:115181.
- [2]. Fredman G, et al. Specialized pro-resolving mediators in vascular inflammation and atherosclerotic cardiovascular disease. Nature reviews. Cardiology. 2024 Nov;21(11):808-823.
