1425050-80-1
1425050-80-1
Chemical Structure
hIgG-hFc receptor-IN-3
- CAS No.: 1425050-80-1
- Formula:C25H27N5O2
- Molecular Weight:429.51
InChIKey: ZEYDULYHSJJDGS-UHFFFAOYSA-N
SMILES: N#CC(C1=NC2=C(N=C1N3CCCCCC3)C=CC=C2)C(NCC4=CC(OC)=CC=C4)=O
Biological Activity: hIgG-hFc receptor-IN-3 is a protein-protein interaction inhibitor of human immunoglobulin G-human neonatal Fc receptor (hIgG-hFcRn). Identified via virtual ligand screening and optimized through structure-activity relationship studies, hIgG-hFc receptor-IN-3 competitively inhibits the binding of IgG to FcRn, thereby accelerating the clearance of endogenous IgG. hIgG-hFc receptor-IN-3 can be used for the research of autoimmune diseases[1].
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hIgG-hFc receptor-IN-3 | hIgG-hFc receptor-IN-3 is a protein-protein interaction inhibitor of human immunoglobulin G-human neonatal Fc receptor (hIgG-hFcRn). Identified via virtual ligand screening and optimized through structure-activity relationship studies, hIgG-hFc receptor-IN-3 competitively inhibits the binding of IgG to FcRn, thereby accelerating the clearance of endogenous IgG. hIgG-hFc receptor-IN-3 can be used for the research of autoimmune diseases. | |||||||||||||||||||||
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