1448189-67-0
1448189-67-0
Chemical Structure
NVS-VHL785
- CAS No.: 1448189-67-0
- Formula:C23H30N4O4S
- Molecular Weight:458.57
InChIKey: WGZJLQXDRGNUFL-AABGKKOBSA-N
SMILES: O=C([C@H]1N(C([C@@H](NC(C)=O)C(C)C)=O)C[C@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2
Biological Activity: NVS-VHL785 is a VHL-binding molecular glue that selectively degrades CDO1. NVS-VHL785 recruits CDO1 to the VHL-cullin-RING ubiquitin ligase complex, inducing ubiquitin-proteasome-dependent degradation of CDO1. NVS-VHL785 can be used for research related to CDO1-mediated diseases[1].
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NVS-VHL785 | NVS-VHL785 is a VHL-binding molecular glue that selectively degrades CDO1. NVS-VHL785 recruits CDO1 to the VHL-cullin-RING ubiquitin ligase complex, inducing ubiquitin-proteasome-dependent degradation of CDO1. NVS-VHL785 can be used for research related to CDO1-mediated diseases. | |||||||||||||||||||||
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