156126-12-4
Chemical Structure
North-methanocarbathymidine
Synonym(s): N-MCT
- CAS No.: 156126-12-4
- Formula:C12H16N2O4
- Molecular Weight:252.27
IUPAC Name: 1-((1S,2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)bicyclo[3.1.0]hexan-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
InChIKey: NOWRLNPOENZFHP-ARHDFHRDSA-N
SMILES: O=C1NC(C(C)=CN1[C@@H]2[C@@]3([H])C[C@@]3(CO)[C@@H](O)C2)=O
Biological Activity: North-methanocarbathymidine (N-MCT) is a potent antiviral agent. North-methanocarbathymidine inhibits DNA synthesis. North-methanocarbathymidine demonstrates potent antiviral activity against HSV-1, HSV-2 and KSHV. North-methanocarbathymidine exhibits anticancer activity against colon adenocarcinoma expressing HSV-tk[1].
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North-methanocarbathymidine | North-methanocarbathymidine (N-MCT) is a potent antiviral agent. North-methanocarbathymidine inhibits DNA synthesis. North-methanocarbathymidine demonstrates potent antiviral activity against HSV-1, HSV-2 and KSHV. North-methanocarbathymidine exhibits anticancer activity against colon adenocarcinoma expressing HSV-tk. | |||||||||||||||||||||
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