1628612-29-2
1628612-29-2
Chemical Structure
Wollamide B
- CAS No.: 1628612-29-2
- Formula:C37H57N9O7
- Molecular Weight:739.90
InChIKey: OXJJMHSZSDGXNW-SCJLKASNSA-N
SMILES: O=C(N[C@H](C(N[C@@H](C(N[C@H](C(N[C@H](C(N[C@@H](C(N1)=O)CCCN)=O)CC(N)=O)=O)C(C)C)=O)CC(C)C)=O)CC(C)C)[C@@H]1CC2=CNC3=CC=CC=C23
Biological Activity: Wollamide B is a naturally occurring cyclic hexapeptide with antimycobacterial activity. Wollamide B inhibits the proliferation of extracellular and intramacrophage Mycobacterium tuberculosis. Wollamide B exhibits cytotoxicity against human tumor cell lines. Wollamide B can be used in research related to bacterial infections[1][2][3].
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Wollamide B | Wollamide B is a naturally occurring cyclic hexapeptide with antimycobacterial activity. Wollamide B inhibits the proliferation of extracellular and intramacrophage Mycobacterium tuberculosis. Wollamide B exhibits cytotoxicity against human tumor cell lines. Wollamide B can be used in research related to bacterial infections. | |||||||||||||||||||||
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References
- [1]. Malekian A, et al. Immune priming reprograms the maggot secretome to enhance anti-Leishmania activity. Scientific Reports. 2026 Sep 10.
- [2]. Asfaw H, et al. An efficient synthetic route for preparation of antimycobacterial wollamides and evaluation of their in vitro and in vivo efficacy. Bioorganic & medicinal chemistry letters. 2018 Sep 15;28(17):2899-2905.
- [3]. Chen YX, et al. Total Synthesis and Antibacterial Study of Cyclohexapeptides Desotamide B, Wollamide B and Their Analogs. Chemistry & biodiversity. 2018 Jan;15(1).
