166374-43-2
Chemical Structure
Epibatidine dihydrochloride
- CAS No.: 166374-43-2
- Formula:C11H15Cl3N2
- Molecular Weight:281.61
IUPAC Name: (1R,2R,4S)-2-(6-chloropyridin-3-yl)-7-azabicyclo[2.2.1]heptane dihydrochloride
InChIKey: DGNNWUINALNROG-ZHQIPATHSA-N
SMILES: ClC1=NC=C([C@@H]2[C@]3([H])N[C@](CC3)([H])C2)C=C1.Cl.Cl
Biological Activity: Epibatidine dihydrochloride is a potent neuronal nicotinic acetylcholine receptor (nAChR) activator. Epibatidine dihydrochloride induces endoplasmic reticulum calcium release through activation of nAChR, which in turn activates the PKC/ERK/HO-1 signaling axis, exerting anti-apoptotic effects by inhibiting ROS production and attenuating mitochondrial depolarization. Epibatidine dihydrochloride can be used in research on neurodegenerative diseases[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Epibatidine dihydrochloride | 99% | Epibatidine dihydrochloride is a potent neuronal nicotinic acetylcholine receptor (nAChR) activator. Epibatidine dihydrochloride induces endoplasmic reticulum calcium release through activation of nAChR, which in turn activates the PKC/ERK/HO-1 signaling axis, exerting anti-apoptotic effects by inhibiting ROS production and attenuating mitochondrial depolarization. Epibatidine dihydrochloride can be used in research on neurodegenerative diseases. | ||||||||||||||||||||
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