1801552-15-7
Chemical Structure
MyD88-IN-4
- CAS No.: 1801552-15-7
- Formula:C44H64N4O4
- Molecular Weight:713.00
SMILES: O=C(N1CCCC1)[C@H](C(C)C)N(CCCC2=CC=CC=C2)C([C@@H]3CC[C@H](CC3)C(N(CCCC4=CC=CC=C4)[C@@H](C(C)C)C(N5CCCC5)=O)=O)=O
Biological Activity: MyD88-IN-4 is a MyD88 inhibitor. MyD88-IN-4 exerts antiviral effects by up-regulating IFN-β, and anti-inflammatory effects by inhibiting pro-inflammatory cytokine production. MyD88-IN-4 prevents MyD88 homodimer formation and its interaction with IRF3/IRF7. MyD88-IN-4 demonstrates efficacy against encephalitic alphavirus infections by reducing viral replication and improving survival in VEEV TC-83-infected mouse models. MyD88-IN-4 can be used for the study of alphavirus infections, bacterial toxin-related diseases, and sepsis[1].
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MyD88-IN-4 | MyD88-IN-4 is a MyD88 inhibitor. MyD88-IN-4 exerts antiviral effects by up-regulating IFN-β, and anti-inflammatory effects by inhibiting pro-inflammatory cytokine production. MyD88-IN-4 prevents MyD88 homodimer formation and its interaction with IRF3/IRF7. MyD88-IN-4 demonstrates efficacy against encephalitic alphavirus infections by reducing viral replication and improving survival in VEEV TC-83-infected mouse models. MyD88-IN-4 can be used for the study of alphavirus infections, bacterial toxin-related diseases, and sepsis. | |||||||||||||||||||||
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