1872379-48-0
Chemical Structure
1,2-Dipalmitoyl-sn-glycerol-d9
- CAS No.: 1872379-48-0
- Formula:C35H59D9O5
- Molecular Weight:577.97
IUPAC Name: (S)-3-hydroxy-2-(palmitoyloxy)propyl hexadecanoate-13,13,14,14,15,15,16,16,16-d9
InChIKey: JEJLGIQLPYYGEE-VYTNNFGRSA-N
SMILES: [2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])CCCCCCCCCCCC(OC[C@@H](OC(CCCCCCCCCCCCCCC)=O)CO)=O
Biological Activity: 1,2-Dipalmitoyl-sn-glycerol-d9 is the deuterated-labeled 1,2-Dipalmitoyl-sn-glycerol (HY-W010736). 1,2-Dipalmitoyl-sn-glycerol is a diacylglycerol that activates PKC. 1,2-Dipalmitoyl-sn-glycerol promotes GLUT4 translocation to the cell surface and recruitment to the plasma membrane of adipocytes. 1,2-Dipalmitoyl-sn-glycerol can be used in research on type 2 diabetes[1][2][3][4][5][6][7].
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1,2-Dipalmitoyl-sn-glycerol-d9 | 1,2-Dipalmitoyl-sn-glycerol-d9 is the deuterated-labeled 1,2-Dipalmitoyl-sn-glycerol (HY-W010736). 1,2-Dipalmitoyl-sn-glycerol is a diacylglycerol that activates PKC. 1,2-Dipalmitoyl-sn-glycerol promotes GLUT4 translocation to the cell surface and recruitment to the plasma membrane of adipocytes. 1,2-Dipalmitoyl-sn-glycerol can be used in research on type 2 diabetes. | |||||||||||||||||||||
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1,2-Dipalmitoyl-sn-glycerol (Standard) | ≥98% | 1,2-Dipalmitoyl-sn-glycerol (Standard) is the analytical standard of 1,2-Dipalmitoyl-sn-glycerol (HY-W010736). This product is intended for research and analytical applications. 1,2-Dipalmitoyl-sn-glycerol is a diacylglycerol that activates PKC. 1,2-Dipalmitoyl-sn-glycerol promotes GLUT4 translocation to the cell surface and recruitment to the plasma membrane of adipocytes. 1,2-Dipalmitoyl-sn-glycerol can be used in research on type 2 diabetes. | ||||||||||||||||||||
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1,2-Dipalmitoyl-sn-glycerol | 98.0% | 1,2-Dipalmitoyl-sn-glycerol is a diacylglycerol that activates PKC. 1,2-Dipalmitoyl-sn-glycerol promotes GLUT4 translocation to the cell surface and recruitment to the plasma membrane of adipocytes. 1,2-Dipalmitoyl-sn-glycerol can be used in research on type 2 diabetes. | ||||||||||||||||||||
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References
- [1]. Tsuchiya A, et al. Diacylglycerol promotes GLUT4 translocation to the cell surface in a PKCε-dependent and PKCλ/ι and -ζ-independent manner. Life sciences. 2013 Aug 14;93(5-6):240-6.
- [2]. Slaga TJ. Safety Assessment of Glyceryl Diesters as Used in Cosmetics.
- [3]. Guzmán E. Effect of the incorporation of nanosized titanium dioxide on the interfacial properties of 1, 2-dipalmitoyl-sn-glycerol-3-phosphocholine Langmuir monolayers. Langmuir. 2017 Oct 10;33(40):10715-25.
- [4]. Nishida Y, et al. Remarkable functions of -3 hydroxy and phosphocholine groups in 1,2-diacyl--glycerolipids to induce clockwise (+)-helicity around the 1,2-diacyl moiety: Evidence from conformation analysis by H NMR spectroscopy. Beilstein journal of organic chemistry. 2017;13:1999-2009.
- [5]. Selim S. 1, 2-Dipalmitoyl phosphatidylcholine, 1, 2-dipalmitoyl phosphatidic acid or 1, 2-dipalmitoyl-sn-glycerol inhibit sporangia formation and promote exponential growth of various Frankia isolates from the Casuarinaceae family. Soil Biology and Biochemistry. 1994 May 1;26(5):569-75.
- [6]. Dorset DL, et al. Polymorphic forms of 1,2-dipalmitoyl-sn-glycerol: a combined X-ray and electron diffraction study. Chemistry and physics of lipids. 1988 Sep;48(1-2):19-28.
- [7]. Crecelius CA, et al. A study of the molecular species of diacylglycerol, phosphatidylcholine and phosphatidylethanolamine and of cholinephosphotransferase and ethanolaminephosphotransferase activities in the type II pneumocyte. Biochimica et biophysica acta. 1984 Sep 12;795(2):247-56.
