1923767-20-7
1923767-20-7
Chemical Structure
EGFR-IN-216
- CAS No.: 1923767-20-7
- Formula:C23H26ClF2N3O5
- Molecular Weight:497.92
InChIKey: WTTGANBTUMYZCB-UHFFFAOYSA-N
SMILES: FC1=CC=C(NC2=C3C=C(OC)C(OCCOCCOCCOCCF)=CC3=NC=N2)C=C1Cl
Biological Activity: EGFR-IN-216 is an epidermal growth factor receptor (EGFR) tyrosine kinase (TK) inhibitor. EGFR-IN-216 inhibits EGFR tyrosine kinase phosphorylation, blocks downstream signaling pathway activation, suppresses cancer cell proliferation and promotes tumor cell apoptosis (apoptosis). EGFR-IN-216 can be used for the research of non-small cell lung cancer[1].
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EGFR-IN-216 | EGFR-IN-216 is an epidermal growth factor receptor (EGFR) tyrosine kinase (TK) inhibitor. EGFR-IN-216 inhibits EGFR tyrosine kinase phosphorylation, blocks downstream signaling pathway activation, suppresses cancer cell proliferation and promotes tumor cell apoptosis (apoptosis). EGFR-IN-216 can be used for the research of non-small cell lung cancer. | |||||||||||||||||||||
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