2043014-84-0
2043014-84-0
Chemical Structure
ML416
- CAS No.: 2043014-84-0
- Formula:C14H15FN2OS2
- Molecular Weight:310.41
IUPAC Name: 2-(3-fluorothiophen-2-yl)-N-methyl-N-(4,5,6,7-tetrahydrobenzo[d]thiazol-2-yl)acetamide
InChIKey: WHNKINPAYLHJBY-UHFFFAOYSA-N
SMILES: O=C(N(C1=NC2=C(S1)CCCC2)C)CC=3SC=CC3F
Biological Activity: ML416 is a broad-spectrum antiviral agent. ML416 inhibits host de novo pyrimidine biosynthesis, and induces a variety of interferon-stimulated genes (ISGs). ML416 can be used for the research of viral infections including alphaviruses, influenza virus, and HIV-1[1][2].
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ML416 | ML416 is a broad-spectrum antiviral agent. ML416 inhibits host de novo pyrimidine biosynthesis, and induces a variety of interferon-stimulated genes (ISGs). ML416 can be used for the research of viral infections including alphaviruses, influenza virus, and HIV-1. | |||||||||||||||||||||
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References
- [1]. Chung DH, et al. Discovery of a Broad-Spectrum Antiviral Compound That Inhibits Pyrimidine Biosynthesis and Establishes a Type 1 Interferon-Independent Antiviral State. Antimicrob Agents Chemother. 2016;60(8):4552-4562. Published 2016 Jul 22. [Content Brief]
- [2]. Jennifer E. Golden, et al. Inhibitors of viruses. WO2016183093A1. 2017-11-11
