212891-05-9
212891-05-9
Chemical Structure
(E)-Cynarin
Synonym(s): (E)-Cynarine;(E)-Plemocil
- CAS No.: 212891-05-9
- Formula:C25H24O12
- Molecular Weight:516.45
IUPAC Name: (1R,3R,4S,5R)-1,3-bis(((E)-3-(3,4-dihydroxyphenyl)acryloyl)oxy)-4,5-dihydroxycyclohexane-1-carboxylic acid
InChIKey: YDDUMTOHNYZQPO-RVXRWRFUSA-N
SMILES: OC(C=C1/C=C/C(O[C@]2(C[C@H]([C@H]([C@@H](C2)O)O)OC(/C=C/C3=CC(O)=C(C=C3)O)=O)C(O)=O)=O)=C(C=C1)O
Biological Activity: (E)-Cynarin ((E)-Cynarine) is the E-isomer of Cynarin (HY-N0359). Cynarin is an anti-asphyxiant with multiple biological activities, possessing antioxidant, antihistamine, and antiviral activities, etc.[1][2]
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(E)-Cynarin | (E)-Cynarin ((E)-Cynarine) is the E-isomer of Cynarin (HY-N0359). Cynarin is an anti-asphyxiant with multiple biological activities, possessing antioxidant, antihistamine, and antiviral activities, etc. | |||||||||||||||||||||
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References
- [1]. Topal M, et al. Antioxidant, antiradical, and anticholinergic properties of cynarin purified from the Illyrian thistle (Onopordum illyricum L.). J Enzyme Inhib Med Chem. 2016;31(2):266-75. [Content Brief]
- [2]. Dong GC, et al. Blocking effect of an immuno-suppressive agent, cynarin, on CD28 of T-cell receptor. Pharm Res. 2009 Feb;26(2):375-81. [Content Brief]
