2237925-69-6
2237925-69-6
Chemical Structure
DMA-155
- CAS No.: 2237925-69-6
- Formula:C20H21N7O
- Molecular Weight:375.43
InChIKey: JZOSCSBUTIVUDD-UHFFFAOYSA-N
SMILES: O=C(C1=C(N)N=C(N(C)C)C(C2=CC=C(C3=CC=CC=C3)C=C2)=N1)NC(N)=N
Biological Activity: DMA-155 is an antiviral agent with binding activity against SARS-CoV-2 5'-terminal stem-loop RNAs, with affinities of 51.1 μM (SL1), 61.1 μM (SL4), 54.5 μM (SL5a), 66.9 μM (SL5b) and 48.6 μM (SL6), respectively. DMA-155 inhibits SARS-CoV-2 viral replication and reduces SARS-CoV-2 viral RNA levels. DMA-155 is applicable to the research of COVID-19[1].
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DMA-155 | DMA-155 is an antiviral agent with binding activity against SARS-CoV-2 5'-terminal stem-loop RNAs, with affinities of 51.1 μM (SL1), 61.1 μM (SL4), 54.5 μM (SL5a), 66.9 μM (SL5b) and 48.6 μM (SL6), respectively. DMA-155 inhibits SARS-CoV-2 viral replication and reduces SARS-CoV-2 viral RNA levels. DMA-155 is applicable to the research of COVID-19. | |||||||||||||||||||||
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