23295-92-3
Chemical Structure
L-2-Phosphoglyceric acid
- CAS No.: 23295-92-3
- Formula:C3H7O7P
- Molecular Weight:186.06
IUPAC Name: (S)-3-hydroxy-2-(phosphonooxy)propanoic acid
InChIKey: GXIURPTVHJPJLF-REOHCLBHSA-N
SMILES: O=C(O)[C@@H](OP(O)(O)=O)CO
Biological Activity: L-2-Phosphoglyceric acid is an endogenous metabolite. L-2-Phosphoglyceric acid serves as a substrate for phosphatases and releases inorganic phosphate upon catalytic dephosphorylation. L-2-phosphoglyceric acid is upregulated in human oral fibroblasts treated with Porphyromonas gingivalis bacterial extracellular vesicles. L-2-Phosphoglyceric acid is useful for research related to prostate cancer and periodontitis[1][2][3][4].
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L-2-Phosphoglyceric acid | L-2-Phosphoglyceric acid is an endogenous metabolite. L-2-Phosphoglyceric acid serves as a substrate for phosphatases and releases inorganic phosphate upon catalytic dephosphorylation. L-2-phosphoglyceric acid is upregulated in human oral fibroblasts treated with Porphyromonas gingivalis bacterial extracellular vesicles. L-2-Phosphoglyceric acid is useful for research related to prostate cancer and periodontitis. | |||||||||||||||||||||
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References
- [1]. SUTHERLAND EW, et al. Mechanism of the phosphoglyceric mutase reaction. J Biol Chem. 1949 Nov;181(1):153-9. [Content Brief]
- [2]. Dong XM, et al. Targeted profiling of polar metabolites in cancer metabolic reprogramming by hydrophilic interaction liquid chromatography-tandem mass spectrometry. Journal of chromatography. A. 2022 Dec 20;1686:463654. [Content Brief]
- [3]. Yip SH, et al. Substrate ambiguous enzymes within the Escherichia coli proteome offer different evolutionary solutions to the same problem. Molecular biology and evolution. 2013 Sep;30(9):2001-12.
- [4]. Haugsten H R, Lipka A, Kristoffersen A K, et al. Metabolic changes in oral fibroblasts after exposure to bacterial extracellular vesicles from three strains of Porphyromonas gingivalis[J]. Cellular Microbiology, 2025, 2025(1): 7515004.
