2417925-65-4
2417925-65-4
Chemical Structure
VR17-04 iodide
- CAS No.: 2417925-65-4
- Formula:C14H15IN2O2
- Molecular Weight:370.19
IUPAC Name: 4-(benzylcarbamoyl)-3-hydroxy-1-methylpyridin-1-ium iodide
InChIKey: CDCRJIWQQSCQJS-UHFFFAOYSA-N
SMILES: [I-].O=C(NCC=1C=CC=CC1)C2=CC=[N+](C=C2O)C
Biological Activity: VR17-04 iodide is an inhibitor of influenza virus RNA synthesis. VR17-04 iodide inhibits viral RNA synthesis by influenza virus polymerase and RNA synthesis by SARS-CoV-2 nsp7/8/12 polymerase, as well as influenza A virus RNA polymerase activity. VR17-04 iodide can be used for research on COVID-19 and influenza[1][2][3].
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VR17-04 iodide | VR17-04 iodide is an inhibitor of influenza virus RNA synthesis. VR17-04 iodide inhibits viral RNA synthesis by influenza virus polymerase and RNA synthesis by SARS-CoV-2 nsp7/8/12 polymerase, as well as influenza A virus RNA polymerase activity. VR17-04 iodide can be used for research on COVID-19 and influenza. | |||||||||||||||||||||
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References
- [1]. Walker AP, et al. Enisamium is a small molecule inhibitor of the influenza A virus and SARS-CoV-2 RNA polymerases. bioRxiv [Preprint]. 2020 Jan 6:2020.04.21.053017. [Content Brief]
- [2]. Elli S, et al. Enisamium Inhibits SARS-CoV-2 RNA Synthesis. Biomedicines. 2021 Sep 17;9(9):1254.
- [3]. Te Velthuis AJW, et al. Enisamium Reduces Influenza Virus Shedding and Improves Patient Recovery by Inhibiting Viral RNA Polymerase Activity. Antimicrobial agents and chemotherapy. 2021 Mar 18;65(4):e02605-20.
