2618349-09-8
2618349-09-8
Chemical Structure
WEE1 degrader-2
- CAS No.: 2618349-09-8
- Formula:C20H14F3N3O4
- Molecular Weight:417.34
InChIKey: XSVUNFLWSUASGN-UHFFFAOYSA-N
SMILES: O=C(N1)CCC(C2=COC3=C2C=C(NC(C4=CC(C(F)(F)F)=NC=C4)=O)C=C3)C1=O
Biological Activity: WEE1 degrader-2 is a Wee1 molecular glue degrader. WEE1 degrader-2 induces ubiquitination and degradation of Wee1 kinase by recruiting the CRBN E3 ubiquitin ligase complex. WEE1 degrader-2 degrades Wee1 protein in tumor cells. WEE1 degrader-2 can be used in research related to acute lymphoblastic leukemia and glioblastoma[1].
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WEE1 degrader-2 | WEE1 degrader-2 is a Wee1 molecular glue degrader. WEE1 degrader-2 induces ubiquitination and degradation of Wee1 kinase by recruiting the CRBN E3 ubiquitin ligase complex. WEE1 degrader-2 degrades Wee1 protein in tumor cells. WEE1 degrader-2 can be used in research related to acute lymphoblastic leukemia and glioblastoma. | |||||||||||||||||||||
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