2631059-91-9
2631059-91-9
Chemical Structure
GSPT1 degrader-28
- CAS No.: 2631059-91-9
- Formula:C23H25N5O2
- Molecular Weight:403.48
InChIKey: DWIDBAPNHVNCEW-UHFFFAOYSA-N
SMILES: O=C(NC1=O)CCN1C2=CN=C(C=C3)N2C=C3C4CCN(CC5=CC=CC=C5)CC4
Biological Activity: GSPT1 degrader-28 is a GSPT1 molecular glue degrader with an EC50 of 0.170 μM. GSPT1 degrader-28 induces ubiquitination and proteasomal degradation of GSPT1 and SALL4 by recruiting the CRBN E3 ubiquitin ligase complex. GSPT1 degrader-28 can be used in cancer-related research[1].
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GSPT1 degrader-28 | GSPT1 degrader-28 is a GSPT1 molecular glue degrader with an EC50 of 0.170 μM. GSPT1 degrader-28 induces ubiquitination and proteasomal degradation of GSPT1 and SALL4 by recruiting the CRBN E3 ubiquitin ligase complex. GSPT1 degrader-28 can be used in cancer-related research. | |||||||||||||||||||||
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