2654076-02-3
2654076-02-3
Chemical Structure
H-APPAMP-023
- CAS No.: 2654076-02-3
- Formula:C24H29F3N8O
- Molecular Weight:502.54
InChIKey: OJMDASWRIMYSTE-QAPCUYQASA-N
SMILES: CC(C1=C2N=C(NC[C@H]3CCNC[C@@H]3O)C=C(NCC4=C(C(F)(F)F)N5C=CC=CC5=N4)N2N=C1)C
Biological Activity: H-APPAMP-023 is a molecular glue. H-APPAMP-023 inhibits CDK activity, with IC50 values of 102 nM and 702 nM for CDK7 and CDK12, respectively[1].
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H-APPAMP-023 | H-APPAMP-023 is a molecular glue. H-APPAMP-023 inhibits CDK activity, with IC50 values of 102 nM and 702 nM for CDK7 and CDK12, respectively. | |||||||||||||||||||||
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