2710-64-7
Chemical Structure
5-Fluoro-2′-deoxy-UTP
- CAS No.: 2710-64-7
- Formula:C9H14FN2O14P3
- Molecular Weight:486.13
InChIKey: YQOCUTDPKPPQGA-RRKCRQDMSA-N
SMILES: O[C@H]1C[C@H](N2C=C(F)C(NC2=O)=O)O[C@@H]1COP(OP(OP(O)(O)=O)(O)=O)(O)=O
Biological Activity: 5-Fluoro-2′-deoxy-UTP can be used as a substrate for DNA synthesis[1].
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5-Fluoro-2′-deoxy-UTP | 5-Fluoro-2′-deoxy-UTP can be used as a substrate for DNA synthesis. | |||||||||||||||||||||
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Thymidine 5′-diphosphate | Thymidine 5′-diphosphate (dTDP) is a key product for pyrimidine synthesis in organisms. Thymidine 5′-diphosphate is generated via the phosphorylation of thymidine 5'-monophosphate (dTMP) catalyzed by thymidylate kinase (TMPK), a process requiring ATP and Mg2+. Thymidine 5′-diphosphate is further catalyzed by TMPK into thymidine 5'-triphosphate (dTTP). Detection of Thymidine 5′-diphosphate levels enables the assessment of TMPK activity. | |||||||||||||||||||||
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5-PA-dUTP | 5-PA-dUTP (5-Propargylamino-dUTP) is a C5-modified nucleotide and can be incorporated into DNA nanoparticles (DNPs) for photosensitizer delivery. 5-PA-dUTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | |||||||||||||||||||||
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5-F-UTP | 5-F-UTP (5-Fluorouridine-5'-triphosphate) is a monomeric raw material that can be used for nucleic acid synthesis. | |||||||||||||||||||||
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Deoxythymidine-5'-triphosphate | Deoxythymidine-5'-triphosphate (dTTP) is a deoxyribonucleoside triphosphate and a thymidine analog, which serves as a direct precursor for DNA synthesis. Deoxythymidine-5'-triphosphate can be used for DNA amplification in the DNA polymerase chain reaction (PCR). Deoxythymidine-5'-triphosphate is also applicable to research related to diseases such as leukemia. | |||||||||||||||||||||
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5-fluoro-dCTP | 5-fluoro-dCTP is a fluorinated pyrimidine dNTP that can be used as a substrate for the incorporation of fluorine modification into specific DNA sequences by primer extension (PEX) catalyzed by Pwo polymerase. | |||||||||||||||||||||
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5-Aminoallyl-dUTP | 5-Aminoallyl-dUTP (5-Aminoallyl 2'-deoxyuridine 5'-triphosphate) is a monomeric raw material that can be used for nucleic acid synthesis. | |||||||||||||||||||||
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dTTPαS | dTTPαS is a monomeric raw material that can be used for nucleic acid synthesis. | |||||||||||||||||||||
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5-BrdUTP sodium salt | 5-BrdUTP sodium salt is a TdT substrate which can be used to label the DNA double-strand breaks. | |||||||||||||||||||||
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dUTP | dUTP (Deoxyuridine triphosphate) is a deoxyuridine phosphate having a triphosphate group at the 5'-position. Dutp can be used in PCR. | |||||||||||||||||||||
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BVDU 5′-Triphosphate | BVDU 5′-Triphosphate is an antivirus agent with 5′-Triphosphate label, targeting viral DNA polymerase. BVDU 5′-Triphosphate shows excellent selectivity against varicella-zoster virus (VZV) and herpes simplex virus type 1 (HSV-1), due to a specific phosphorylation by the virus-encoded thymidine kinase. | |||||||||||||||||||||
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