2741952-21-4
2741952-21-4
Chemical Structure
Cap-dependent endonuclease-IN-27
- CAS No.: 2741952-21-4
- Formula:C23H19F2N3O4
- Molecular Weight:439.41
InChIKey: IYONRGIGIMDOIP-VQTJNVASSA-N
SMILES: O=C1N(C)[C@@]2([H])N(N3C1=C(O)C(C=C3)=O)[C@H](C4=CC=CC=C4)C5=CC(F)=C(F)C=C5OCC2
Biological Activity: Cap-dependent endonuclease-IN-27 (Compound 8) is an orally active potent cap-dependent endonuclease (CEN) inhibitor. Cap-dependent endonuclease-IN-27, an antiviral agent, shows activity against influenza B virus. Cap-dependent endonuclease-IN-27 has inhibitory activity against IFV A/WSN/33 (H1N1) polymerase (EC50 = 12.26 nM)[1].
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Cap-dependent endonuclease-IN-27 | Cap-dependent endonuclease-IN-27 (Compound 8) is an orally active potent cap-dependent endonuclease (CEN) inhibitor. Cap-dependent endonuclease-IN-27, an antiviral agent, shows activity against influenza B virus. Cap-dependent endonuclease-IN-27 has inhibitory activity against IFV A/WSN/33 (H1N1) polymerase (EC50 = 12.26 nM). | |||||||||||||||||||||
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