2762110-71-2
2762110-71-2
Chemical Structure
Pestalotinone B
- CAS No.: 2762110-71-2
- Formula:C21H20Cl2O5
- Molecular Weight:423.29
IUPAC Name: 2,4-dichloro-7,9-dihydroxy-1-methoxy-3-methyl-10-(3-methylbut-2-en-1-yl)dibenzo[b,e]oxepin-11(6H)-one
InChIKey: FERJMWBEYPSSTC-UHFFFAOYSA-N
SMILES: O=C1C2=C(OC)C(Cl)=C(C(Cl)=C2OCC3=C(O)C=C(O)C(=C13)CC=C(C)C)C
Biological Activity: Pestalotinone B is a chlorinated, 12-O-methylated benzophenone antibiotic that can be isolated from marine-derived Pestalotiopsis strains. Pestalotinone B exhibits antibacterial activity against Staphylococcus aureus and Enterococcus faecium. Pestalotinone B can be used in research on bacterial infections[1][2][3].
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Pestalotinone B | Pestalotinone B is a chlorinated, 12-O-methylated benzophenone antibiotic that can be isolated from marine-derived Pestalotiopsis strains. Pestalotinone B exhibits antibacterial activity against Staphylococcus aureus and Enterococcus faecium. Pestalotinone B can be used in research on bacterial infections. | |||||||||||||||||||||
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References
- [1]. Deprez BE, et al. Studies toward Pestalachloride B: Synthesis of the 6/7/6 Tricyclic Scaffold. Organic letters. 2026 Mar 06;28(9):2831-2835.
- [2]. Jiang P, et al. Recent advances on Pestalotiopsis genus: chemistry, biological activities, structure-activity relationship, and biosynthesis. Archives of pharmacal research. 2023 Jun;46(6):449-499.
- [3]. Jiang Z, et al. Pestalotinones A-D, new benzophenone antibiotics from endophytic fungus Pestalotiopsis trachicarpicola SC-J551. The Journal of antibiotics. 2022 Apr;75(4):207-212. [Content Brief]
