2767053-65-4
Chemical Structure
Forsyshiyanine A
- CAS No.: 2767053-65-4
- Formula:C17H25NO
- Molecular Weight:259.39
InChIKey: NGZYENNZZWWFIR-GVDBMIGSSA-N
SMILES: [H][C@@]12CCC3=NC(C)=CC=C3[C@]1(CCC[C@@]2(CO)C)C
Biological Activity: Foryshiyanine A is a triterpenoid alkaloid. Foryshiyanine A possesses anti-inflammatory activity, inhibiting the release of β-glucuronidase from rat polymorphonuclear leukocytes. Foryshiyanine A exhibits antiviral activity, with an EC50 of 4.5 μM against respiratory syncytial virus (RSV) and an IC50 of 7.3 μM against influenza A virus (H1N1). Foryshiyanine A reduces viral load by disrupting viral replication and entry. Foryshiyanine A may be used for the researches of inflammation and infection[1][2].
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Forsyshiyanine A | Foryshiyanine A is a triterpenoid alkaloid. Foryshiyanine A possesses anti-inflammatory activity, inhibiting the release of β-glucuronidase from rat polymorphonuclear leukocytes. Foryshiyanine A exhibits antiviral activity, with an EC50 of 4.5 μM against respiratory syncytial virus (RSV) and an IC50 of 7.3 μM against influenza A virus (H1N1). Foryshiyanine A reduces viral load by disrupting viral replication and entry. Foryshiyanine A may be used for the researches of inflammation and infection. | |||||||||||||||||||||
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References
- [1]. Zhao L, et al. Alkaloids bearing rare skeletons from Forsythia suspensa with anti-inflammatory and anti-viral activities in vitro. Phytochemistry. 2021;186:112739. [Content Brief]
- [2]. Rfaish SY, et al. Semisynthesis of Forsyshiyanine A and a Derivative with Significant Anti-Pancreatic Cancer Activity. J Nat Prod. 2025;88(11):2781-2788. [Content Brief]
