2816903-43-0
2816903-43-0
Chemical Structure
RBM39 Degrader-3
- CAS No.: 2816903-43-0
- Formula:C17H12F3N3O2S
- Molecular Weight:379.36
InChIKey: DDHHQAQCISMBHY-UHFFFAOYSA-N
SMILES: CC1=C2C(C(F)F)=CNC2=C(NS(=O)(C3=CC(C#N)=CC(F)=C3)=O)C=C1
Biological Activity: RBM39 degrader-3 is a molecular glue. RBM39 degrader-3 promotes the ubiquitination and proteasomal degradation of the splicing factor RBM39 by recruiting DCAF15 to the CRL4 E3 ubiquitin ligase complex (with an EC50 < 5 μM for inducing the formation of the DCAF15-RBM39 ternary complex). RBM39 degrader-3 can be used in research on colorectal cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
RBM39 Degrader-3 | RBM39 degrader-3 is a molecular glue. RBM39 degrader-3 promotes the ubiquitination and proteasomal degradation of the splicing factor RBM39 by recruiting DCAF15 to the CRL4 E3 ubiquitin ligase complex (with an EC50 < 5 μM for inducing the formation of the DCAF15-RBM39 ternary complex). RBM39 degrader-3 can be used in research on colorectal cancer. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
