2832888-22-7
Chemical Structure
308-R hydrochloride
- CAS No.: 2832888-22-7
- Formula:C23H24ClFN6O4S
- Molecular Weight:534.99
IUPAC Name: (R)-2-fluoro-5-methyl-N-(4-(4-(morpholin-2-ylmethoxy)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)phenyl)benzenesulfonamide hydrochloride
InChIKey: HIHXQRDSHOLDDO-UNTBIKODSA-N
SMILES: CC1=CC=C(C(S(=O)(NC2=CC=C(C=C2)C3=NC(OC[C@H]4CNCCO4)=C5C=NNC5=N3)=O)=C1)F.Cl
Biological Activity: 308-R hydrochloride is a SGK3/SGK1/S6K1 inhibitor. 308-R hydrochloride exhibits an IC50 of 5 nM against human SGK3, an IC50 of 10 nM against human SGK1, and an IC50 of 1 nM against human S6K1. 308-R hydrochloride can be used in breast cancer research. 308-R hydrochloride is also applicable to studies related to PROTAC synthesis, such as serving as the target protein ligand for PROTAC SGK3 degrader-2 (HY-176823)[1].
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308-R hydrochloride | 308-R hydrochloride is a SGK3/SGK1/S6K1 inhibitor. 308-R hydrochloride exhibits an IC50 of 5 nM against human SGK3, an IC50 of 10 nM against human SGK1, and an IC50 of 1 nM against human S6K1. 308-R hydrochloride can be used in breast cancer research. 308-R hydrochloride is also applicable to studies related to PROTAC synthesis, such as serving as the target protein ligand for PROTAC SGK3 degrader-2 (HY-176823). | |||||||||||||||||||||
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