288862-58-8
288862-58-8
Chemical Structure
Oleoyl oxazolopyridine
- CAS No.: 288862-58-8
- Formula:C24H36N2O2
- Molecular Weight:384.56
IUPAC Name: (Z)-1-(oxazolo[4,5-b]pyridin-2-yl)octadec-9-en-1-one
InChIKey: YMLAXVVBJJHSKD-KTKRTIGZSA-N
SMILES: C(CCCCCCC/C=C\CCCCCCCC)(=O)C1=NC=2C(O1)=CC=CN2
Biological Activity: Oleoyl oxazolopyridine is a fatty acid amide hydrolase (FAAH) inhibitor with a Ki of 1.3-2.3 nM. Oleoyl oxazolopyridine blocks the hydrolysis of Anandamide (HY-10863). Oleoyl oxazolopyridine can be used in research related to lipid metabolism, inflammation, and pain[1][2][3].
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Oleoyl oxazolopyridine | Oleoyl oxazolopyridine is a fatty acid amide hydrolase (FAAH) inhibitor with a Ki of 1.3-2.3 nM. Oleoyl oxazolopyridine blocks the hydrolysis of Anandamide (HY-10863). Oleoyl oxazolopyridine can be used in research related to lipid metabolism, inflammation, and pain. | |||||||||||||||||||||
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References
- [1]. Boger DL, et al. Exceptionally potent inhibitors of fatty acid amide hydrolase: the enzyme responsible for degradation of endogenous oleamide and anandamide. Proceedings of the National Academy of Sciences of the United States of America. 2000 May 09;97(10):5044-9.
- [2]. Rakers C, et al. Stable isotope liquid chromatography-tandem mass spectrometry assay for fatty acid amide hydrolase activity. Analytical biochemistry. 2012 Feb 15;421(2):699-705.
- [3]. Prasansuklab A, et al. Ethanolic extract of Streblus asper leaves protects against glutamate-induced toxicity in HT22 hippocampal neuronal cells and extends lifespan of Caenorhabditis elegans. BMC complementary and alternative medicine. 2017 Dec 28;17(1):551.
