Oleoyl oxazolopyridine
Oleoyl oxazolopyridine is a fatty acid amide hydrolase (FAAH) inhibitor with a Ki of 1.3-2.3 nM. Oleoyl oxazolopyridine blocks the hydrolysis of Anandamide (HY-10863). Oleoyl oxazolopyridine can be used in research related to lipid metabolism, inflammation, and pain.
For research use only. We do not sell to patients.
- CAS No.: 288862-58-8
- Formula: C24H36N2O2
- Molecular Weight:384.56
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
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hFAAH 24.3 nM (IC50) |
hFAAH 1.3 nM (Ki) |
rFAAH 2.3 nM (Ki) |
In Vitro
Oleoyl oxazolopyridine inhibits recombinant human FAAH expressed in COS-7 membranes with a Ki of 1.3 nM[1].
Oleoyl oxazolopyridine (1-500 nM; 5-10 min) is a partial non-competitive inhibitor of recombinant human FAAH, with an IC50 of 24.3 nM[2].
Oleoyl oxazolopyridine (50 nM) almost completely inhibits FAAH-mediated d4-EA formation in human and dog liver microsomes[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 288862-58-8
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Molecular Weight 384.56
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Formula C24H36N2O2
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SMILES
C(CCCCCCC/C=C\CCCCCCCC)(=O)C1=NC=2C(O1)=CC=CN2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Oleoyl oxazolopyridine Related Classifications
HY-131702 Related Classifications
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