2925268-86-4
Chemical Structure
AMT-NHS
- CAS No.: 2925268-86-4
- Formula:C22H21NO7S
- Molecular Weight:443.47
IUPAC Name: tert-butyl ((1R,2R,3R,4S)-2-bromo-3-hydroxy-4-(hydroxymethyl)cyclopentyl)carbamate
InChIKey: OOLVYUSWNMDHMP-UHFFFAOYSA-N
SMILES: O=C(ON1C(CCC1=O)=O)CCSCC2=C(C)OC(C(C)=C3O4)=C2C=C3C(C)=CC4=O
Biological Activity: AMT-NHS is an RNA-protein crosslinker. AMT-NHS consists of a psoralen derivative and an N-hydroxysuccinimide ester group, which react with RNA bases and primary amines of proteins, respectively. AMT-NHS penetrates live yeast cells and crosslinks Cbf5 to H/ACA snoRNAs with high specificity. AMT-NHS induces distinct crosslinking patterns and targets both single-stranded and double-stranded regions of RNA. AMT-NHS can be used to capture various RNA-protein interactions in cells[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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AMT-NHS | 98.70% | AMT-NHS is an RNA-protein crosslinker. AMT-NHS consists of a psoralen derivative and an N-hydroxysuccinimide ester group, which react with RNA bases and primary amines of proteins, respectively. AMT-NHS penetrates live yeast cells and crosslinks Cbf5 to H/ACA snoRNAs with high specificity. AMT-NHS induces distinct crosslinking patterns and targets both single-stranded and double-stranded regions of RNA. AMT-NHS can be used to capture various RNA-protein interactions in cells. | ||||||||||||||||||||
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