2930694-64-5
2930694-64-5
Chemical Structure
GSPT1 degrader-20
- CAS No.: 2930694-64-5
- Formula:C23H23N3O4
- Molecular Weight:405.45
InChIKey: FUISFNJDBUZNFR-UHFFFAOYSA-N
SMILES: O=C(N1)CCC(N2CC3=C(C=CC(CC(NCCC4=CC=CC=C4)=O)=C3)C2=O)C1=O
Biological Activity:
GSPT1 degrader-20 is a cereblon (CRBN)-recruiting molecular glue degrader (with a
DC50 < 1 nM against GSPT1 HiBiT) that promotes the ubiquitination and proteasomal degradation of GSPT1 and/or IKZF1. GSPT1 degrader-20 can be used in research on hematological malignancies such as acute lymphoblastic leukemia[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
GSPT1 degrader-20 | GSPT1 degrader-20 is a cereblon (CRBN)-recruiting molecular glue degrader (with a DC50 < 1 nM against GSPT1 HiBiT) that promotes the ubiquitination and proteasomal degradation of GSPT1 and/or IKZF1. GSPT1 degrader-20 can be used in research on hematological malignancies such as acute lymphoblastic leukemia. |
|||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
