2951082-10-1
Chemical Structure
Antifungal agent 188
- CAS No.: 2951082-10-1
- Formula:C12H11F3N6O
- Molecular Weight:312.25
InChIKey: JBMOAOIPKWJQJL-DENHBWNVSA-N
SMILES: NC1=C(/C=N/NC2=CC=C(OC(F)(F)F)C=C2)C(N)=NC=N1
Biological Activity: Antifungal agent 188 is an Antifungal agent. Antifungal agent 188 exhibits weak inhibitory activity against E. coli PDHc-E1, with IC50 = 59.7 μM. Antifungal agent 188 induces extensive ultrastructural damage in fungal hyphae, disrupting the cell wall and cell membrane. Antifungal agent 188 causes mitochondrial dysfunction and impaired energy production. Antifungal agent 188 induces ROS accumulation. Antifungal agent 188 interferes with glucan-related carbohydrate processes, reduces β-glucan (HY-W145521) content, and impairs cell wall integrity. Antifungal agent 188 is a potent in vitro inhibitor of M. fructicola and B. cinerea. Antifungal agent 188 can be used for research on peach brown rot[1].
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Antifungal agent 188 | Antifungal agent 188 is an Antifungal agent. Antifungal agent 188 exhibits weak inhibitory activity against E. coli PDHc-E1, with IC50 = 59.7 μM. Antifungal agent 188 induces extensive ultrastructural damage in fungal hyphae, disrupting the cell wall and cell membrane. Antifungal agent 188 causes mitochondrial dysfunction and impaired energy production. Antifungal agent 188 induces ROS accumulation. Antifungal agent 188 interferes with glucan-related carbohydrate processes, reduces β-glucan (HY-W145521) content, and impairs cell wall integrity. Antifungal agent 188 is a potent in vitro inhibitor of M. fructicola and B. cinerea. Antifungal agent 188 can be used for research on peach brown rot. | |||||||||||||||||||||
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