3026985-75-8
3026985-75-8
Chemical Structure
CRBN modulator-2
- CAS No.: 3026985-75-8
- Formula:C21H19N3O5
- Molecular Weight:393.39
InChIKey: MNOPHTXOYIDKKA-UHFFFAOYSA-N
SMILES: O=C(C1=CC(OC)=CC=C1)NC2=CC=C3C(N(C4C(NC(CC4)=O)=O)CC3=C2)=O
Biological Activity: CRBN modulator-2 is a molecular glue that binds to cereblon (CRBN) in the CRL4 E3 ligase complex (IC50 < 1 μM for binding to CRBN). CRBN modulator-2 can be used in research on hematological malignancies such as multiple myeloma and acute myeloid leukemia[1].
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CRBN modulator-2 | CRBN modulator-2 is a molecular glue that binds to cereblon (CRBN) in the CRL4 E3 ligase complex (IC50 < 1 μM for binding to CRBN). CRBN modulator-2 can be used in research on hematological malignancies such as multiple myeloma and acute myeloid leukemia. | |||||||||||||||||||||
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