3031321-95-3
3031321-95-3
Chemical Structure
Influenza virus-IN-10
- CAS No.: 3031321-95-3
- Formula:C26H26N4O2
- Molecular Weight:426.51
InChIKey: ANXMFVBDYRWUCA-UHFFFAOYSA-N
SMILES: O=C(C1=C(NC(CNC2=C(C)C=CC=C2)=O)C=CC=C1)NCCC3=C4C=CNC4=CC=C3
Biological Activity: Influenza virus-IN-10 is a dual-target antiviral agents for influenza that targets both PAC (KD = 8.9 μM) and NP (KD = 52.5 μM) simultaneously. Influenza virus-IN-10 exhibits an EC50 values of 1.64 μM) against influenza A virus (H1N1, A/WSN/33) and broad-spectrum activity against other influenza strains, including influenza B virus and multiple subtypes of influenza A[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Influenza virus-IN-10 | Influenza virus-IN-10 is a dual-target antiviral agents for influenza that targets both PAC (KD = 8.9 μM) and NP (KD = 52.5 μM) simultaneously. Influenza virus-IN-10 exhibits an EC50 values of 1.64 μM) against influenza A virus (H1N1, A/WSN/33) and broad-spectrum activity against other influenza strains, including influenza B virus and multiple subtypes of influenza A. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Zhang C, et al. Novel benzamide derivatives with indole moiety as dual-target antiviral agents: Rational design, efficient synthesis, and potent anti-influenza activity through concurrent binding to PAC terminal domain and viral nucleoprotein. Eur J Med Chem. 2025 Sep 5;293:117681. [Content Brief]
