30511-77-4
30511-77-4
Chemical Structure
Isochavicine
- CAS No.: 30511-77-4
- Formula:C17H19NO3
- Molecular Weight:285.34
IUPAC Name: (2E,4Z)-5-(benzo[d][1,3]dioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one
InChIKey: MXXWOMGUGJBKIW-MFDSWNTHSA-N
SMILES: O=C(N1CCCCC1)/C=C/C=C\C2=CC=C(OCO3)C3=C2
Biological Activity: Isochavicine is a TRPV1 and TRPA1 activator with EC50 values of 3.4 µM and 71.1 µM, respectively. Isochavicine is an alkaloid that can be isolated from Piper longum L. Isochavicine inhibits the growth of cress and barnyardgrass. Isochavicine can be used in research on leishmaniasis[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Isochavicine | 93.21% | Isochavicine is a TRPV1 and TRPA1 activator with EC50 values of 3.4 µM and 71.1 µM, respectively. Isochavicine is an alkaloid that can be isolated from Piper longum L. Isochavicine inhibits the growth of cress and barnyardgrass. Isochavicine can be used in research on leishmaniasis. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Okumura Y, et al. Activation of TRPV1 and TRPA1 by black pepper components. Bioscience, biotechnology, and biochemistry. 2010;74(5):1068-72.
- [2]. Suwitchayanon P, et al. Phytotoxic property of Piper retrofractum fruit extracts and compounds against the germination and seedling growth of weeds. Acta Physiologiae Plantarum. 2019 Mar;41(3):33.
- [3]. Kozukue N, et al. Kinetics of light-induced cis-trans isomerization of four piperines and their levels in ground black peppers as determined by HPLC and LC/MS. Journal of agricultural and food chemistry. 2007 Aug 22;55(17):7131-9.
- [4]. Tsuboi S, et al. A facile synthesis of 3,4-dienamides by the reaction of propargyl alcohols with cyclic amide acetals and their stereoselective rearrangement to 2(E),4(Z)-dienamides promoted with alumina. Total synthesis of isochavicine. J Org Chem. 1984 Apr;49(7):1204-1208.
