3052745-46-4
3052745-46-4
Chemical Structure
PROTAC K-Ras Degrader-6
- CAS No.: 3052745-46-4
- Formula:C57H65F2N11O5
- Molecular Weight:1022.19
InChIKey: GIBHYBDXJQVMRG-UHFFFAOYSA-N
SMILES: C#CC1=C(C=CC2=CC(O)=CC(C3=NC=C4C(N5CC6CCC(N6)C5)=NC(OCCN7CCC(CC7)CC8CCN(CC8)CC9CCN(CC9)C%10=CC%11=C(N(C(N%11C)=O)C%12CCC(NC%12=O)=O)C=C%10)=NC4=C3F)=C21)F
Biological Activity: PROTAC K-Ras Degrader-6 is a PROTAC degrader targeting K-Ras that recruits KRas for ubiquitination and proteasomal degradation. PROTAC K-Ras Degrader-6 binds to cereblon, thereby ubiquitinating KRas. PROTAC K-Ras Degrader-6 can be used in cancer research[1].
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PROTAC K-Ras Degrader-6 | PROTAC K-Ras Degrader-6 is a PROTAC degrader targeting K-Ras that recruits KRas for ubiquitination and proteasomal degradation. PROTAC K-Ras Degrader-6 binds to cereblon, thereby ubiquitinating KRas. PROTAC K-Ras Degrader-6 can be used in cancer research. | |||||||||||||||||||||
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